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And the response of target tissues e.g. bone ; 25 ; . Not surprisingly, a number of independent studies from around the world have shown that there appears to be vitamin D deficiency in a subset of the elderly population, characterized by low blood levels of 25-OH-D coupled with elevations in plasma PTH and alkaline phosphatase 26 ; . There is evidence that this vitamin D deficiency contributes to declining bone mass and increases the incidence of hip fractures 27 ; . Although some of these studies may exaggerate the extent of the problem by focusing on institutionalized individuals or inpatients with decreased sun exposures, in general they have forced health professionals to re-address the vitamin D intake of this segment of society and look at potential solutions to correct the problem. Table 3.1 presents the findings of several studies that found that modest increases in vitamin D intakes between 10 and 20 mg day ; reduce the rate of bone loss and the incidence of hip fractures. These findings have led several agencies and researchers to suggest an increase in recommended vitamin D intakes for the elderly from 2.5 5 mg day to a value that is able to maintain normal 25-OH-D levels in the elderly, such as 1015 mg day. This vitamin D intake results in lower rates of bone loss and is proposed for the middle-aged 5070 years ; and old-aged 70 years ; populations 33 ; . The increased requirements are justified mainly on the grounds of the reduction in skin synthesis of vitamin D, a linear reduction occurring in both men and women that begins with the thinning of the skin at age 20 years 24 and ceftin and avapro, because avapor 30 mg.

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What is in this leaflet. Read this leaflet carefully before taking AVAPRO. This leaflet answers some common questions about AVAPRO. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. Do not throw this leaflet away. You may need to refer to it again later. Always follow the instructions that your doctor and pharmacist give you about AVAPRO. If you have any concerns about taking AVAPRO, ask your doctor or pharmacist. What is AVAPRO AVAPRO is a trade name manufacturer's name ; for the medicine, irbesartan. This medicine is in the tablets your doctor has prescribed for you. What AVAPRO is used for AVAPRO lowers high blood pressure, which doctors call hypertension Your doctor measured your blood pressure and found it to be too high. Everyone has blood pressure. This pressure helps get your blood all around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension high blood pressure ; which means your blood pressure stays high, even when you are calm and relaxed. There are usually no symptoms of high blood pressure. The only way of knowing that you have hypertension is to have your blood pressure checked on a regular basis. High blood pressure, if not treated, can damage blood vessels in several organs such as the heart, the kidneys, the brain and the eyes. This may lead to heart attacks, heart or kidney failure, strokes, or blindness. There are usually no symptoms of high blood pressure before damage occurs, so your doctor needs to measure your blood pressure to see if it is too high. High blood pressure can be treated and controlled with medicines such as AVAPRO. Your doctor may also have recommended that you adjust your lifestyle to help to lower your high blood pressure losing weight, avoiding smoking, reducing alcohol consumption and restricting the amount of salt in the diet ; . Your doctor may also have encouraged the practice of regular, mild not strenuous ; exercise such as walking, swimming, etc. AVAPRO is also used in the treatment of kidney disease in patients with high blood pressure and type 2 diabetes.

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